Endocrine Abstracts

Background: Interindividual variation in thyroid hormone concentrations is greater than intraindividual variation, suggesting that individuals have different set-points for pituitary–thyroid axis function. Variation in thyroid hormone levels within the normal range has clinical effects and is associated with a number of clinical parameters such as bone mass, BMI, metabolic parameters, and heart rate. The aim of this study was therefore to gain a better insight into the de...

Sex steroid concentrations have a strong genetic determination, but environmental factors and body composition play an important role. Intrauterine growth restriction, evidenced by low birth weight has been associated with altered gonadotropin metabolism. If this relationship is also present across the wide range of birth weight is unkown. Serum sex steroid concentrations were investigated in healthy young brothers in relation to birth weight, body composition and parental ste...

Background: We have previously shown that a higher BMI and less favorable body composition are associated with relatively higher FT3 levels (within the euthyroid range) in healthy young men. In this study, we aimed to investigate whether FT3 and the ratio FT3:FT4 are also associated with cardiovascular markers in a healthy euthyroid population of middle-aged men and women.Methods: Thyroid parameters were measur...